Keywords: Pulse Sequence Design, Multi-Contrast
Motivation: Existing 3D multi-parametric imaging methods suffers from long scan times, and decent MRA contrasts are yet to be provided.
Goal(s): To develop a 3-minute 3D high resolution multi-parametric imaging method that offeres whole brain imaging with TOF quality MRA results.
Approach: A simplified version of the MULTIPLEX method, namely MULTIPLEX-Lite, is proposed. Compared to the original MULTIPLEX method, addtional MRA results are offered, while removing the T1 and PD mappings to further improve scan time.
Results: The proposed MULTIPLEX-Lite method offered whole brain high resolution (<1mm3 voxel volume) MRA, PDW, T1W, aT1W, SWI, R2* maps and QSM in one 3-minute scan.
Impact: The proposed MULTIPLEX-Lite method is among the most feasible and practical solutions for routine clinically friendly 3D high-resolution multi-parametric imaging practices.
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