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Abstract #0582

High-resolution free-breathing simultaneous myocardial T1, T2 and T1ρ mapping with region-optimized virtual coils (ROVir)

Zhenfeng Lyu1,2, Sha Hua3, Peng Hu1,2, and Haikun Qi1,2
1School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, 2Shanghai Clinical Research and Trial Center, Shanghai, China, 3Department of Cardiovascular Medicine, Ruijin Hospital Lu Wan Branch, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Synopsis

Keywords: Myocardium, Cardiomyopathy, Quantitative Imaging

Motivation: Cardiac parametric mapping with electrocardiogram-triggered single-shot acquisition has compromised spatial resolution due to limited quiescent period for data acquisition.

Goal(s): To develop a high-resolution simultaneous myocardial T1, T2 and T1ρ mapping technique.

Approach: Enhance the spatial resolution while reducing the FOV to make the acquisition window fit in the mid-diastolic quiescent period in the cardiac cycle. Subsequently, employ the ROVir technique to eliminate fold-over artifacts arising from FOV reduction.

Results: The proposed technique achieved high-resolution multi-parametric mapping without a loss of quantitative precision.

Impact: A novel framework was proposed to shorten the acquisition window and improve the spatial resolution of electrocardiogram-triggered cardiac parametric mapping beyond common k-space undersamping. High-resolution myocardial parametric mapping can provide more precise and reliable diagnostic information.

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