Keywords: Heart Failure, Myocardium, pulmonary hypertension; electromechanical discoordination;
Motivation: Non-invasive and accurate evaluation of right ventricular (RV) function in pulmonary arterial hypertension (PAH) is of urgent need in clinical practice.
Goal(s): To investigate the clinical implications of RV electromechanical dyssynchrony which were non-invasively derived from cardiac MRI.
Approach: Calculate systolic stretch fraction (SSF) and diastolic relaxation fraction (DRF) based on strain MRI and test their prognostic values in an observation prospective PAH cohort.
Results: SSF-RV-Longitudinal could independently predict the clinical worsening.
Impact: The present study first reported SSF-RV-Longitudinal as a novel parameter to evaluate RV function, which could predict the clinical worsening in PAH patients.
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