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Abstract #0607

Mitigating Geometric Distortion & Susceptibility Artifacts in cDTI via SAP-M2-EPI: A feasibility study

Mehdi Sadighi1, Danielle Kara1, Dingheng Mai1, Khoi Nguyen1, Shi Chen1, Deborah Kwon1, and Christopher Nguyen1
1Cardiovascular Innovation Research Center (CIRC), Heart, Vascular, and Thoracic Institute, Cleveland Clinic, Cleveland, OH, United States

Synopsis

Keywords: Myocardium, Heart, cardiac diffusion, Motion compensated gradients, Aliasing, geometric distortion, PROPELLER MRI

Motivation: We aimed to enhance in vivo cardiac diffusion tensor imaging (cDTI), a technique challenged by limitations, especially in high-BMI patients, causing notable aliasing and distortion issues.

Goal(s): Our primary goal was to introduce and validate Short-Axis-PROPELLER-M2-EPI (SAP-M2-EPI) for cDTI. The focus was on reducing aliasing and distortion artifacts while ensuring robust motion correction.

Approach: SAP-M2-EPI combines motion-compensated diffusion gradients with PROPELLER, effectively minimizing motion artifacts and suppressing aliasing and distortion.

Results: Our study shows that SAP-M2-EPI successfully mitigates motion artifacts and significantly reduces aliasing and distortion, particularly beneficial for high-BMI patients. This innovative approach holds great promise for enhancing cDTI diagnostic accuracy.

Impact: Impact: SAP-M2-EPI’s success offers clinicians a potent tool for enhancing cDTI diagnoses, especially in high-BMI patients. It opens doors to in-depth cardiac research, encourages further methodological innovations, and ultimately promises better patient care through more accurate imaging.

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