Keywords: Myocardium, Myocardium, motion compensation, gradient moment nulling
Motivation: Cardiac diffusion tensor imaging (cDTI) based on spin-echo employs up to 2nd order (M2) motion compensated diffusion gradients. It is unclear whether higher order motion compensation would be beneficial.
Goal(s): To evaluate the impact of higher order motion compensation (i.e. velocity, acceleration, jerk, snap, crackle and pop) in cDTI.
Approach: Diffusion gradient waveforms with M1 to M6 motion compensation were designed and implemented in a prospective study of healthy volunteers. Mean diffusivity and fractional anisotropy maps were quantitatively evaluated.
Results: Significant reductions in MD and MD heterogeneity were observed in the M6 relative to M2 compensated data.
Impact: We demonstrate the potential importance of compensating for higher orders of motion (>M2) in cardiac diffusion MRI. This work may inform gradient waveform design for more accurate and robust cardiac diffusion MRI.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords