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Abstract #0623

Accelerating Quantitative MRI using Self-supervised Deep Learning with Model Reinforcement

Wanyu Bian1,2, Albert Jang1,2, and Fang Liu1,2
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Quantitative Imaging, Quantitative Imaging, Model-based Reconstruction, Relaxometry, Brain, Self-supervised Learning

Motivation: Quantitative MRI (qMRI) is time-consuming and requires substantial efforts for acceleration to cut down the acquisition time.

Goal(s): This paper proposes a novel self-supervised learning framework that uses model reinforcement, RELAX-MORE, for accelerated qMRI reconstruction.

Approach: The proposed method uses an optimization algorithm to unroll an iterative model-based qMRI reconstruction into a deep learning framework, enabling accelerated MR parameter maps that are highly accurate and robust.

Results: The proposed method generates high quality MR parameter maps that correct for image artifacts, removes noise, and recovers image features in regions of imperfect image conditions.

Impact: This work demonstrates the feasibility of a new self-supervised learning method for rapid MR parameter mapping, that is readily adaptable to the clinical translation of qMRI.

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Keywords