Keywords: IVIM, Brain
Motivation: The assumption of Gaussian diffusion in the extravascular space in the IVIM model does not necessarily hold, especially for neuronal tissues.
Goal(s): To mitigate the impacts on IVIM estimation from complicated extravascular space diffusion such as in the crossing-fiber tissues.
Approach: We employed Spherical Tensor Encoding (STE) in place of the Linear Tensor Encoding (LTE) as in the conventional Stejskal-Tanner experiment to eliminate the orientational dependence of diffusion signal.
Results: The feasibility of the microscopic IVIM based on STE experiments was demonstrated in both healthy and diseased participants, with expected contrasts according to known anatomy/pathology.
Impact: A new framework of IVIM measurement was proposed based on the Linear Tensor Encoding diffusion experiment. The proposed approach can achieve diffusivity estimates in one excitation, which will otherwise require acquisition of multiple diffusion weighting directions.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords