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Abstract #0680

Physically and Anatomically Constrained Self-Supervised Motion Correction for Free-Breathing Cardiac T1 Mapping

Eyal Hanania1, Ilya Volovik2, Israel Cohen1, and Moti Freiman1
1The Technion – Israel Institute of Technology, Haifa, Israel, 2Bnai Zion medical center, Haifa, Israel, Haifa, Israel

Synopsis

Keywords: Myocardium, Machine Learning/Artificial Intelligence, Motion Correction

Motivation: Cardiac T1 mapping is often limited by the need for breath-holding to prevent motion artifacts, which restricts its use in patients who cannot hold their breath.

Goal(s): To create a self-supervised deep learning method for motion-corrected, free-breathing cardiac T1 mapping without requiring large datasets or worrying about data variability.

Approach: We present a new self-supervised model that combines a signal relaxation model with anatomical constraints and employs the voxel-morph framework for motion correction. Our model's performance was assessed using a publicly available myocardial T1 mapping dataset.

Results: Our approach outperformed other state-of-the-art registration methods in terms of R2, DICE, and Hausdorff distance.

Impact: Our model offers the possibility of extending cardiac T1 mapping to patients who cannot perform breath-hold MRI procedures by ensuring robust motion correction for accurate T1 mapping, all without the necessity for large training datasets or worries about data anomalies.

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Keywords