Keywords: Myocardium, Cardiomyopathy
Motivation: LGE and ECV are standard cardiac MR (CMR) techniques for detecting focal and diffuse myocardial fibrosis, requiring gadolinium contrast agents. For patients with gadolinium contraindications, non-contrast CMR techniques are needed to detect myocardial fibrosis.
Goal(s): To evaluate the performance of endogenous T1ρ dispersion imaging for myocardial fibrosis.
Approach: A recently proposed free-breathing T1ρ dispersion imaging technique was employed to image patients with non-ischemic cardiomyopathies. The endogenous parameters, T1ρ, myocardial fibrosis index (mFI), and native T1 were evaluated against LGE and ECV.
Results: T1ρ and mFI were elevated in the LGE region and mFI showed the best correlation with ECV among the tested parameters.
Impact: T1ρ dispersion imaging is a promising CMR technique for detecting myocardial fibrosis without exogenous contrast agents.
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