Keywords: Liver, Diffusion/other diffusion imaging techniques
Motivation: Single-shot and multi-shot M1-optimized diffusion imaging (MODI) are recent DWI methods used to mitigate motion and distortion artifacts, yet they often experience chemical shift-based fat suppression failures in the abdomen.
Goal(s): To optimize fat suppression in multi-shot MODI-DWI of the abdomen.
Approach: Slice-specific chemical shift-encoded (CSE) data-informed optimization of shims is combined with single-shot and multi-shot MODI-DWI in 7 subjects imaged at 3T.
Results: Improved fat suppression and water signal excitation were observed alongside the motion and distortion artifact reduction provided by multi-shot MODI-DWI. Unwanted fat signal was reduced through this technique in areas of interest such as the liver, spleen, and ribcage.
Impact: Motion-robust, low-distortion DWI of the abdomen, with reliable fat suppression is demonstrated by combining multi-shot EPI, M1-optimized DW waveforms, and an optimized slice-by-slice shimming approach. This combined method may enable improved detection and staging of cancer in the abdomen.
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