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Abstract #0728

Utilizing Synthetic MRI and Deep Learning Reconstruction of DWI to Distinguish Benign from Malignant Breast Lesions

Wanjun Xia1, Yong Zhang1, Kaiyu Wang2, Guiyong Liu2, Zhenghao Cao1, and Jingliang Cheng1
1Department of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2MR Research China, GE Healthcare, Beijing, China

Synopsis

Keywords: Breast, Cancer, Deep Learning Reconstruction, Diffusion-Weighted Imaging, Breast Diagnosis, Synthetic MRI

Motivation: Breast cancer has emerged as the foremost global malignancy, prompting a growing inclination toward exploring novel non-invasive imaging techniques that obviate the need for contrast agent administration.

Goal(s): Enhancing breast diagnostics without reliance on contrast agents.

Approach: Expanding on the foundation of deep learning-based DWI reconstruction, coupled with Synthetic MRI, as a viable alternative to traditional contrast-enhanced diagnostic methodologies, the focus lies in pinpointing valuable parameters for differential diagnosis.

Results: The fusion of deep learning-reconstructed DWI and Synthetic MRI yields an impressive AUC (Area Under the Curve) of 0.995 in distinguishing between benign and malignant breast pathologies.

Impact: The integration of deep learning-reconstructed DWI with Synthetic MRI not only carries substantial diagnostic significance in discerning between benign and malignant breast conditions but also exhibits the promise of supplanting conventional contrast-enhanced methodologies.

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Keywords