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Abstract #0757

High resolution 3D isotropic non-rigid motion compensated T1 Dixon of Liver at a hybrid PET-MR scanner

Jake Penney1,2, Khalid Ambarki1, Aurélien Monnet1, Hatem Necib3,4, Valérie Vilgrain5,6, Karl-Philipp Kunze7,8, René Michael Botnar7,9, Claudia Prieto7,9, and Ralph Sinkus2,7
1Siemens Healthcare France, Courbevoie, France, 2INSERM U1148 Laboratory for vascular translational science, Paris, France, 3CHU de Nantes, Nantes, France, 4UMR_S 1307 Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers, Nantes, France, 5Hôpital Beaujon AP-HP, Clichy, France, 6INSERM U1149 Centre de Recherche sur l'Inflammation, Paris, France, 7School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, 8MR Research Collaborations, Siemens Healthcare GmbH, Frimley, United Kingdom, 9Escuela de Ingeniería, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Motion Correction, Motion Correction, MRI, PET-MRI, liver, navigator, HCC, cancer, free-breathing MRI

Motivation: In current clinical practice, liver MRI scans often suffer from motion artifacts. This issue typically arises because patients struggle to maintain breath-holding.

Goal(s): Our goal is to produce a high-quality, isotropic 3D Dixon T1 scan without the need for breath-holding.

Approach: . Our method involves using a navigator to estimate liver motion, enabling us to calculate non-rigid motion fields for image reconstruction

Results: This approach yields high-quality free-breathing isotropic T1 3D Dixon liver data with a voxel size of 1.3mm³, surpassing the quality of the gold standard non-isotropic breath-hold Dixon T1 liver scan.

Impact: This work aims to deliver previously unseen high-quality free-breathing isotropic 3D Dixon liver data that can surpass the current clinical standard breath-hold non-isotropic T1 3D Dixon liver scans.

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Keywords