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Abstract #0776

Simultaneous Multiparametric Quantitative MRI for Abdominal Imaging in a Single Breath-hold with MRF-EPTI

Di Cui1, Zhen J Wang1, Yan Li1, Duan Xu1, Peder E.Z. Larson1, and Xiaoxi Liu1
1Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States

Synopsis

Keywords: Kidney, New Trajectories & Spatial Encoding Methods, Abdomen

Motivation: Multiparametric mapping is essential in the assessment of renal physiology and
physiopathology, while the conventional quantitative MR methods requires long acquisition
time and multiple breath-hold periods.

Goal(s): To develop an efficient simultaneous multiparametric quantification method for abdomen imaging.

Approach: MRF-EPTI technique was applied for quantitative abdomen imaging. The repeatability was evaluated by in-vivo scans on two healthy volunteers. Motion sensitivity was evaluated with/without breath-hold.

Results: Simultaneous multiparametric quantification of T1, T2, T2*, proton density and quantitative susceptibility mapping including susceptibility source separation for abdominal imaging was achieved in a single breath-hold time (16s).

Impact: We acquired simultaneous multiparametric quantification of T1, T2, T2*, proton density and quantitative susceptibility mapping including susceptibility source separation, and generated high-quality multi-contrast synthetic images for abdominal imaging in a single breath-hold with MRF-EPTI technique.

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Keywords