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Abstract #0826

Machine learning and the prediction of enlarged lateral ventricular postnatal development trend in fetuses with isolated ventriculomegaly

Xue Chen1, Zhou Huang2, Peng Wu3, Jibin Zhang1, and Yonggang Li2
1Department of Radiology, the Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Suzhou, China, 2Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou, China, 3Philips Healthcare, Shanghai, China

Synopsis

Keywords: Fetal, Machine Learning/Artificial Intelligence

Motivation: To evaluate the intracranial structures and distinct components (grew matter [GM] and white matter [WM]) adjacent to the occipital horn of the lateral ventricle T2WI radiomics features in healthy fetuses and fetuses with ventriculomegaly (FVs),

Goal(s): and to predict postnatal changes in the size of the enlarged lateral ventricle in FVs.

Approach: Utilizing WM-radiomics on the affected sides of FVs, the SVM algorithm effectively predicted the changes in ventricle size,

Results: as evidenced by the highest area under the curve (AUC) values of 0.771 and 0.738 in both the training and validation sets based on DeLong’s test (all P < 0.05).

Impact: An MRI-based occipital WM-radiomics model holds the potential to predict trends in changing ventriculomegaly.The image-based predictive model exhibits applicability in prenatal care. Leveraging image analysis and machine learning techniques may provide further insight into the pathophysiologic features of ventriculomegaly.

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