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Abstract #0854

Hybrid Multidimensional MRI: Demonstrating Repeatability in Non-Invasive Prostate Cancer Tissue Characterization

Abel Lorente Campos1, Aritrick Chatterjee1, Ambereen Yousuf1, Tatjana Antic2, Aytekin Oto1, and Gregory Karczmar1
1Radiology, University of Chicago, Chicago, IL, United States, 2Pathology, University of Chicago, Chicago, IL, United States

Synopsis

Keywords: Prostate, Prostate

Motivation: Validate the consistency and reliability of Hybrid Multidimensional MRI (HM-MRI) through repeatability assessments.

Goal(s): Evaluate the repeatability of HM-MRI in prostate tissue characterization and its diagnostic accuracy for prostate cancer.

Approach: Our approach consists on performing dual HM-MRI scans with a one-week interval to assess measurement consistency and diagnostic accuracy of HM-MRI biomarkers.

Results: The results indicate high reproducibility of HM-MRI metrics, evidenced by strong inter-class correlation coefficients, with consistent tissue composition measurements across initial and repeat scans, and robust diagnostic performance of HM-MRI parameters in prostate cancer detection.

Impact: The findings of this study highlights the potential of HM-MRI as a reliable tool for prostate cancer diagnosis, paving the way for non-invasive clinical applications and inspiring further research into its utility in other diagnostic imaging techniques.

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