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Abstract #0872

MIROR: The Clinical Decision Support System with Functional Imaging and Machine Learning

Dadi Zhao1,2, Sara Burling2, Lesley MacPherson3, Lara Worthington1,2,4, Theodoros N Arvanitis1,2,5, John R Apps1,2, and Andrew C Peet1,2
1Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom, 2Oncology, Birmingham Children's Hospital, Birmingham, United Kingdom, 3Radiology, Birmingham Children's Hospital, Birmingham, United Kingdom, 4RRPPS, University Hospital Birmingham NHS Foundation Trust, Birmingham, United Kingdom, 5Engineering, University of Birmingham, Birmingham, United Kingdom

Synopsis

Keywords: Diagnosis/Prediction, Radiomics

Motivation: Radiomics has potential to bring added values to cancer diagnosis and prognosis, whilst a practical tool that is accessible for clinicians and radiologists has not been available.

Goal(s): To design MIROR, a clinical decision support system, that can aid tumour diagnosis with real-time image and spectroscopy analysis.

Approach: The project keeps collecting childhood brain tumour proton MR images and spectroscopy in England and has built a multi-centre database that includes 377 cases.

Results: MIROR supports key features including visualisation, image analysis, feature extraction, spectroscopy quantification, and tumour type and subtype prediction through machine learning.

Impact: A practical solution that translates radiomics and machine learning into clinical scenarios can aid tumour diagnosis and treatment planning, bring benefits to patient healthcare, and improve clinical outcomes.

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