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Abstract #0875

Accelerating Low-Field Prostate DWI: Self-Supervised Denoising for Rapid Scan Acquisition

Laura Pfaff1,2, Omar Darwish2, Cornelius Eichner2, Fabian Wagner1, Mareike Thies1, Nastassia Vysotskaya1, Elisabeth Weiland2, Thomas Benkert2, Marcel Dominik Nickel2, Tobias Wuerfl2, and Andreas Maier1
1Pattern Recognition Lab, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany, 2Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany

Synopsis

Keywords: Analysis/Processing, Low-Field MRI, Diffusion-Weighted Imaging

Motivation: Diffusion-weighted imaging (DWI) is crucial for lesion detection but suffers from inherently low signal-to-noise ratio (SNR), especially in low-field settings.

Goal(s): The goal of this work is to accelerate low-field prostate DWI, reducing the number of image repetitions and scan time while maintaining image quality.

Approach: We present a self-supervised denoising method employing Stein's unbiased risk estimator (SURE) and a physics-based noise model and evaluate the denoising results without relying on ground-truth data.

Results: Our method excels in preserving image content, outperforming other denoising techniques. This allows a substantial reduction in scan time, making it a promising advancement in low-field DWI.

Impact: Our proposed denoising approach accelerates low-field prostate DWI via self-supervised denoising, improving scan efficiency without compromising image quality. We further demonstrate how to employ a physics-based noise model to evaluate denoising performance in the absence of noise-free ground-truth data.

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Keywords