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Abstract #0880

AtlasSeg: Atlas Prior Guided Dual-UNet for Cortical Segmentation in Fetal Brain MRI

Haoan Xu1, Tianshu Zheng1, Xinyi Xu1, Yao Shen1, Jiwei Sun1, Cong Sun2, Guangbin Wang3, and Dan Wu1
1Department of Biomedical Engineering, Zhejiang University, Hangzhou, China, 2Department of Radiology, Beijing Hospital, Beijing, China, 3Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

Synopsis

Keywords: Analysis/Processing, Segmentation, Fetal Brain MRI; Artificial Intelligence

Motivation: Automatic segmentation of fetal brain remains challenging partially due to the dynamically changing anatomical structures during fetal brain development.

Goal(s): To enhance segmentation accuracy through incorporating gestational age-specific information as a guidance, we introduce AtlasSeg, a dual-U-shape network with dense attentive interactions.

Approach: By providing atlas volume and segmentation label at the corresponding gestational age, AtlasSeg effectively extracts the contextual features of age-specific patterns and structures that assist segmentations.

Results: AtlasSeg demonstrated superior performance against six other segmentation networks in both standard and out-of-distribution experiments, in two fetal MRI datasets. Ablation tests further demonstrated the role of atlas guidance.

Impact: Through gestational age-specific atlas-guided information, AtlasSeg can serve as an accurate and robust automatic segmentation tool for its superior performance in both in-distribution and out-of-distribution tests, which is useful for quantitative analysis in large-scale fetal brain studies.

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