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Abstract #0908

Concept 0.13 T bedside MRI for early brain imaging in the neonatal intensive care unit.

Aaron R. Purchase1,2,3, Monika Sliwiak1, Sara V. Bates3,4, Jason P. Stockmann1,3, Martin D. Hurlimann1,3, Lawrence L. Wald1,3,5, and Clarissa Z. Cooley1,3
1A.A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 2Radiology, Massachusetts General Hospital, Boston, MA, United States, 3Harvard Medical School, Boston, MA, United States, 4Pediatrics-Neonatology, Massachusetts General Hospital, Boston, MA, United States, 5Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, United States

Synopsis

Keywords: Magnets (B0), Magnets (B0)

Motivation: Despite the high diagnostic value of MRI, safety concerns and logistical burdens often prohibit the transport of neonatal intensive care unit (NICU) patients to standard MRI scanners.

Goal(s): In response, we aim to design a specialized NICU bedside MRI scanner that prioritizes minimal disruption to care and provides a higher field strength (and signal-to-noise) than currently available portable scanners.

Approach: Using realistic finite element modeling and genetic algorithm optimization, we demonstrate a 131mT Halbach magnet design with a peak-to-peak homogeneity of 421ppm over a 14cm diameter spherical volume.

Results: We present the computer-aided-design prototype of the full portable NICU MRI system.

Impact: The bedside MRI scanner capable of diffusion contrast neuroimaging of neonates could bring a new early evaluation tool for brain conditions such as hypoxic ischemic encephalopathy (HIE).

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