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Abstract #1057

High-resolution mapping of hand innervation: novel approaches at 7T MRI

Pauline Coralie Guillemin1, David Ferreira Branco2, Yacine M'Rad1, Loan Mattera3, Orane Lorton1, Pierre-Alexandre Poletti2, Gian-Franco Piredda4,5, Antoine Klausser4,5, Roberto Martuzzi3, Rares Salomir2, and Sana Boudabbous2
1Image guided Interventions Laboratory (949), Faculty of Medicine, University of Geneva, Geneva, Switzerland, 2Radiology Department, University Hospitals of Geneva, Geneva, Switzerland, 3Fondation Campus Biotech Geneva, Geneva, Switzerland, 4Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, 5CIBM Centre for Biomedical Imaging, Geneva, Switzerland

Synopsis

Keywords: Peripheral Nerves, Nerves, Pacinian corpuscles

Motivation: Exploit the high resolution provided by the 7T MRI technology to detect fine structures in the hand.

Goal(s): To create an atlas of hand structures, with a specific focus on nerves and Pacinian corpuscles. This atlas is intended to serve both diagnostic purposes and to support reconstructive surgical procedures.

Approach: An ethics committee was obtained to scan volunteers using 7T MRI. Post-processing was carried out to delineate the nerve fiber network and mechanoreceptors.

Results: We successfully reconstruct and describe the anatomy of all nerve fibers from the carpus to the digital nerve division, as well as the Pacinian corpuscles, for three healthy volunteers.

Impact: A visual interactive “Hand Nerves Atlas” matching morphology and fiber tracking of hand nerves on high-field will be delivered to the scientific community for fundamental research, to clinicians for microscopic surgery of nerves, and for educational purposes in medical schools.

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Keywords