Abstract #1070

Phase jolt: Second spatial derivative of phase images is a new contrast that offers many benefits for SWI type processing

Omer Faruk Gulban^1,2, Andreas Deistung³, Desmond Ho Yan Tse⁴, Saskia Bollmann⁵, Renzo Huber⁶, Rainer Goebel^1,2, Kendrick Kay⁷, and Dimo Ivanov¹

¹Department of Cognitive Neuroscience, Maastricht Univesity, Faculty of Psychology and Neuroscience, Maastricht, Netherlands, ²Brain Innovation, Maastricht, Netherlands, ³Polyclinic for Radiology, University Hospital Halle, Halle, Germany, ⁴Scannexus, Maastricht, Netherlands, ⁵School of Electrical Engineering and Computer Science, The University of Queensland, Brisbane, Australia, ⁶National Institutes of Health, Washington DC, MD, United States, ⁷Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, United States

Synopsis

Keywords: Image Reconstruction, Contrast Mechanisms, Phase

Motivation: Unlike magnitude images, even simple averaging is difficult with phase images, because of the circular nature of phase, spanning 2pi radians range.

Goal(s): In our research that uses mesoscopic imaging (< 0.5 mm isotropic) at 7 T, we need to average multiple acquisitions to increase SNR. Being unable to average straightforwardly together with the lack of natural zero point is a critical constraint.

Approach: To address this problem, we propose to operate on the magnitude of the second spatial derivative of phase images - called “phase jolt”.

Results: Our results show phase jolt offers benefits for processing associated with SWI imaging.

Impact: Phase jolt is an easy to implement new contrast where vessels and non brain tissue are highlighted and background bias field is mitigated. Therefore, phase jolt images have potential to be impactful in any setting where phase images are used.

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