Keywords: Magnetization Transfer, Magnetization transfer, qMT, ihMT, brain microstructure
Motivation: To improve the accuracy of quantitative Magnetization Transfer (qMT) for interrogation of brain microstructure.
Goal(s): To determine: i) the model for qMT that best describes the signal from MT and inhomogeneous MT (ihMT) experiments, and ii) the MT preparations that contribute useful data.
Approach: We tested accuracies of the models based on fit quality in-vivo and ex-vivo, comparing ex-vivo qMT at physiological and room temperatures. Data were retrospectively reduced to test the importance of types of MT preparations.
Results: We recommend a model with two bound-pool T2 values and use of different MT pulse widths and duty cycles as a result.
Impact: Our results will impact the model and data acquired for quantitative Magnetization Transfer (qMT) of brain tissues. Use of a two bound-pool model with distinct T2 values and data inputs with variations in MT pulse width and DC is recommended.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords