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Abstract #1150

3D/4D Ultrashort Echo Time Balanced-SSFP MR Lung Images Reconstructed Using XD-GRASP-Pro

William J Garrison1, Zachary Miller2, John P Mugler III1,2, Jing Cai3, and G Wilson Miller1,2,4
1Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, 2Radiology and Medical Imaging, University of Virginia, Charlottesville, VA, United States, 3Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong, 4Physics, University of Virginia, Charlottesville, VA, United States

Synopsis

Keywords: Image Reconstruction, Sparse & Low-Rank Models

Motivation: Obtaining high-quality images of the lung using proton MRI is challenging due to breathing motion and the short T2* and low proton density of lung parenchyma.

Goal(s): Our goal was to demonstrate a free-breathing proton lung MRI approach that maximizes parenchyma and vessel signal in the lungs.

Approach: This method combines a 3D ultra-short echo time (UTE) balanced steady-state free precession (bSSFP) pulse sequence with a GRASP-Pro-based reconstruction algorithm applied to respiratory phase-binned data.

Results: Image quality was markedly better for SSFP images than for spoiled images, and end-of-exhalation frames reconstructed from 4D images compared favorably with respiratory-triggered images.

Impact: A UTE bSSFP radial pulse sequence combined with temporally-constrained reconstruction produces high-signal, high-resolution lung images at end-of-exhalation collected during free breathing. While non-end-of-exhalation reconstruction was less effective, a similar reconstruction algorithm that incorporates motion fields could improve results.

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Keywords