Keywords: Myocardium, Cardiovascular
Motivation: Prognostic value of radiomic features extracted from CMR cine image remains to be investigated.
Goal(s): To evaluate the prognostic value of radiomic features derived from cine images in patients with ST-segment elevation myocardial infarction (STEMI).
Approach: Radiomic features were extracted from CMR cine images on STEMI patients, and LASSO -Cox regression used to select predictive features for MACE. Cox regression was applied to build models.
Results: RAD score provided an incremental prognostic value above baseline clinical factors and LVEF (C-index 0.78 vs 0.69; p=0.002) and outperformed the addition of CMR markers of infarct injury (C-index: 0.78 vs 0.69, p<0.001).
Impact: Radiomic features provide incremental prognostic value to clinical and infarct size in the prediction of MACE, which would promote the development of the prognostic assessment with non-contrast enhanced CMR.
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