Abstract #1178

Association Between Epicardial Adipose Tissue volume and Microvascular Obstruction in Patients with STEMI

Dan Mu¹, Jinxuan Zhao², Hongming Yu¹, Jing Liang¹, Biao Xu², Xiance Zhao³, Xiuzheng Yue⁴, Zhongping Zhang³, and Bing Zhang¹

¹Department of Radiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China, Nanjing, China, ²Department of Cardiology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China, Nanjing, China, ³Philips Healthcare, Shanghai, China, ⁴Philips Healthcare, Beijing, China

Synopsis

Keywords: Inflammation, Infiltration, Cardiovascular, CMR

Motivation: Microvascular obstruction (MVO) after primary percutaneous coronary intervention (pPCI) is identifed as an independent risk factor for poor prognosis in patients with acute myocardial infarction (AMI). However, the clinical implications of Epicardial adipose tissue (EAT) in microvascular obstruction formation in patients with ST-segment elevation myocardial infarction (STEMI) remain unclear.

Goal(s): This study aimed to evaluate the correlation between EAT and MVO volume detected by CMR in STEMI patients.

Approach: Cardiac magnetic resonance (CMR) has emerged as the gold standard technique to detect the extent of MVO and evaluate EAT volume.

Results: Left atrioventricular EAT mass index is an independent predictor of MVO.

Impact: Measurement of EAT using CMR could be used for risk stratification and may be a promising target in developing new therapies to reduce myocardial reperfusion injury in patients with STEMI.

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