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Abstract #1258

Time-Resolved pCASL MRA Using A Multi-Echo 3D-Radial SPGR Sequence

Andreas Petrovic1,2, Martin Soellradl1,2, Thomas Okell3, Leon Lai1,2, Shalini A Amukotuwa1,2, and Roland Bammer1,2
1Department of Diagnostic Imaging, Monash Health, Melbourne, Australia, 2Department of Radiology, Monash University, Melbourne, Australia, 3Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom

Synopsis

Keywords: Arterial Spin Labelling, Arterial spin labelling

Motivation: To improve signal, spatial and temporal resolution, and acquisition time for time resolved ASL imaging for cerebral angiography.

Goal(s): To exploit a time-resolved multi-echo radial 3D ASL sequence to acquire ASL MRA data in a shorter amount of time.

Approach: We performed three flip angle optimized scans with a 1, 2, and 3 echo readout, respectively, and compared image quality and acquisition time.

Results: Using a 3-echo readout, scan time could be reduced from 9:32 min to 6:23 min, without the loss of image quality. Multi-echo scans even showed more details than in the single-echo case.

Impact: Multi-echo 3D radial ASL angiography enables substantial scan time reduction for high-resolution time-resolved cerebral angiography. This will improve clinical applicability and scanner throughput, avoid the use of contrast agents, and is of direct benefit to patients.

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Keywords