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Abstract #1273

UTE-Based DW-SSFP MRI for 7T

Kwan-Jin Jung1
1Beckman Institute, Biomedical Imaging Center, University of Illinois at Urbana-Champaign, Urbana, IL, United States

Synopsis

Keywords: Diffusion Acquisition, Diffusion Tensor Imaging, DW-SSFP

Motivation: At 7T the conventional spin-echo EPI diffusion sequence suffers from the B1+ inhomogeneity and geometric distortion due to refocusing RF pulses and EPI readout.

Goal(s): To develop a diffusion imaging sequence without refocusing RF pulses and EPI readout at 7T.

Approach: Develop a 3-dimensional DW-SSFP sequence with a spiral readout to reduce the geometric distortion, to maximize the diffusion gradient time, and to reduce susceptibility effect.

Results: The proposed DW-SSFP sequence was successful in reducing the B1+ inhomogeneity, the geometric distortion, and the susceptibility effect compared to the spin-echo EPI diffusion sequence using cadaveric head specimens at 7T.

Impact: This sequence enables the acquisition of high-resolution diffusion images that do not suffer from the B1+ inhomogeneity and geometric distortion often observed at 7T. It provides good quality fiber tracts and fractional anisotropy maps of the brain.

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