Keywords: Thermometry/Thermotherapy, MR-Guided Interventions, Liver, Motion Correction, Radial MRI, Focused Ultrasound
Motivation: MRI thermometry faces challenges in moving tissues: intra- and inter-scan motion, limited spatio-temporal resolution, and constrained spatial coverage. These obstacles result in temperature mis-calculations, compromising treatment safety and efficacy.
Goal(s): To develop an image-navigated 3D thermometry method to simultaneously track respiratory motion and temperature in moving tissue.
Approach: A stack-of-radial sequence was combined with compressed sensing reconstruction to obtain dynamic 3D images. An image-navigated multi-baseline proton resonance frequency shift (PRF) method was developed to generate motion-resolved temperature maps with tissue tracking.
Results: The proposed method achieved 24-30 slice coverage with a temporal resolution <1 second/volume and mean absolute error <2 degrees during motion.
Impact: The proposed method could improve the safety and efficacy of MRI-guided thermal therapies through reliable temperature monitoring in moving tissues. The capability to simultaneously track motion and temperature evolution enables feedback control, including focused ultrasound beam steering in moving organs.
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