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Abstract #1280

Real-time automatic multipoint temperature regulation during MRI-guided Laser-induced Thermotherapy (MR-LITT)

Manon Desclides1,2, Valéry Ozenne1, Pierre Bour2, Guillaume Machinet3, Christophe Pierre3, Stéphane Chemouny2, and Bruno Quesson1
1University of Bordeaux, CNRS, CRMSB, UMR 5536, IHU Liryc, Bordeaux, France, 2Certis Therapeutics, Pessac, France, 3ALPhANOV, Talence, France

Synopsis

Keywords: MR-Guided Interventions, MR-Guided Interventions, LITT, laser, ablation, thermometry

Motivation: Current Laser devices used during MR-guided LITT can use single or multiple fibers to create coagulation necrosis, but do not provide opportunities for precise temperature control in tissue.

Goal(s): We present an automatic control algorithm combined with a multi-source laser that allows the temperature to be forced to follow predefined temperature profiles.

Approach: Fast, multi-slice thermometric data are processed on the fly to achieved efficient volumetric temperature regulation of multiple laser sources simultaneously.

Results: We offer a precise and rapid volumetric temperature control solution combined with multi-source LITT to create conformal ablation volumes larger than those achieved with a single fiber.

Impact: Automatic volumetric temperature regulation of multisource LITT combined with real-time multislice MRI thermometry allows better control of local thermotherapies in soft tissues.

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