Keywords: MR-Guided Interventions, Data Acquisition, Lesion Characterization, Radiofrequency ablation, 3D High-resolution Imaging, 3D Cone Trajectory
Motivation: MRI-guided arrhythmia interventions require fast, high-resolution 3D images for comprehensive intraprocedural assessment of radio-frequency ablation lesion size and depth.
Goal(s): Demonstrate similar volumetric lesion quantification between ground-truth respiratory-navigated Cartesian imaging and a novel free-breathing 3D cone-trajectory sequence.
Approach: 4 healthy Yorkshire swine were ablated inside the MRI scanner, with 12 lesions prescribed in total. Volumetric analysis was performed for both Cartesian and 3D cones imaging.
Results: Non-contrast T1-weighted 3D cones imaging with a highly accelerated scan time less than two minutes demonstrated similar lesion volumes to the slower 3D Cartesian sequence.
Impact: Currently, non-contrast ablation lesion assessment in patients requires 5-10 minutes, depending on breathing patterns. The free-breathing 3D cone trajectory sequence presented here is a time-efficient method for lesion characterization that is feasible for intraprocedural applications.
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