Keywords: Relaxometry, Metabolism, High-Field MRI；Magnetic Resonance Fingerprinting
Motivation: The monitoring of brain glucose metabolism plays an important role in the diagnosis of neurological diseases.
Goal(s): The glucose uptake and clearance in the mouse brain were monitored following intravenous administration of glucose using magnetic resonance fingerprinting.
Approach: A magnetic resonance fingerprinting imaging sequence was developed to simultaneously measure the T1, T2 and T1ρ of tissue.
Results: With the intravenous administration of glucose, there was a rapid increase followed by a gradual decrease in R1, R2 and R1ρ values in the brain.
Impact: The application of magnetic resonance fingerprinting in the study of brain glucose metabolism facilitates rapid and simultaneous measurement of multiple parameters, thereby yielding valuable information for the diagnosis of brain-related diseases.
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