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Abstract #1340

Reproducibility of intracranial vascular pulsatility on 3D cine black-blood MRI

Kaiyu Zhang1, William Kerwin2, Xiaodong Ma3, Xin Wang4, Yin Guo1, Thomas Hatsukami5, Mahmud Mossa-Basha2, Chun Yuan2,3, and Niranjan Balu2
1Department of Bioengineering, University of Washington, Seattle, WA, United States, 2Department of Radiology, University of Washington, Seattle, WA, United States, 3Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States, 4Electrical and Computer Engineering, University of Washington, Seattle, WA, United States, 5Department of Surgery, University of Washington, Seattle, WA, United States

Synopsis

Keywords: Vessel Wall, Vessels, Cine Vessel Wall Imaging

Motivation: This research investigates the lesser-explored domain of lumen area changes in intracranial vascular pulsatility, providing insight into cerebral vasculature's mechanical behavior.

Goal(s): To employ cine black-blood MRI for delineating and quantifying intracranial artery pulsatility by monitoring cardiac cycle-induced lumen variations.

Approach: We utilized a sophisticated vessel analysis system to discern pulsatility within the lumen and adjacent tissues, validating our findings with reproducibility scans.

Results: Cine black-blood imaging successfully visualized intracranial vascular pulsatility. The method displayed robust reproducibility in detecting lumen area changes, proving comparable to velocity pulsatility measurements.

Impact: This study illuminates the often-overlooked aspect of lumen area pulsatility, with implications for a holistic assessment of vascular health and disease.

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