Keywords: Blood Vessels, Permeability
Motivation: Evaluating intracranial aneurysm (IA) risk holds significant clinical importance. Recent studies have proposed wall permeability (Ktrans) as a significant risk predictor, but its validity in non-saccular aneurysms remains unclear.
Goal(s): Our study aims to predict non-saccular IA rupture by Ktrans from DCE-MRI.
Approach: Ktrans was derived from the extended Kety/Tofts model. We analyzed correlation between Ktrans and IA size, the Population, Hypertension, Age, Size, Earlier Subarachnoid Hemorrhage, and Site (PHASES) score and other clinical factors.
Results: Ktrans significantly related to IA size and PHASES score, but there was no correlation between Ktrans and intramural hematoma (IMH) and wall enhancement index (WEI).
Impact: By analyzing correlation between aneurysm wall permeability (Ktrans) and other risk factors of non-saccular aneurysms rupture, we found that Ktrans might be a risk indicator for rupture of non-saccular IAs.
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