Keywords: Vascular, Cardiovascular, vessel compliance, white matter, laminar, deep white matter
Motivation: Compliance of the cerebral microvasculature is critical for brain hemodynamics but remains challenging to measure due to the complex cerebral vascular architecture and limitations in imaging technology.
Goal(s): This study aims to utilize high-resolution VASO MRI across cardiac cycles to quantify microvascular compliance at 7T.
Approach: Vascular compliance (VC) was defined as the ratio of CBV changes to changes in blood pressure across a cardiac cycle, which was proportional to the change in rCBV.
Results: The middle layer of grey matter exhibits lower VC than superficial and deep layers. While higher VC was observed in the white matter (WM), especially deep WM.
Impact: The proposed high-resolution VASO MRI offers a promising noninvasive method for estimating cerebral microvascular compliance.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords