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Abstract #1394

Cerebral microbleed detection on susceptibility weighted imaging using solely artificial training data

Jonathan A. Disselhorst1,2,3, Caroline Hall4, Punith B Venkategowda5, Alessandra Griffa4, Vincent Dunet2, Tobias Kober1,2,3, Gilles Allali4, and Bénédicte Maréchal1,2,3
1Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, 2Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 3LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 4Leenaards Memory Centre, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 5Siemens Healthcare Pvt. Ltd., Bangaluru, India

Synopsis

Keywords: Diagnosis/Prediction, Machine Learning/Artificial Intelligence, microbleed, ARIA, SWI

Motivation: Cerebral microbleeds (CMBs) are small brain hemorrhages detectable with MRI associated with conditions like cerebral amyloid angiopathy. As their detection can be difficult, automated methods are needed for quick and precise detection and localization of CMBs.

Goal(s): To propose an algorithm to detect CMBs.

Approach: A neural network was trained on SWI/T2* images, with artificial bleeds generated and added during training. The model’s performance was tested on an independent test set with actual CMBs.

Results: Despite the absence of real CMBs in the training data, the simulated bleeds provided sufficient information to train a model with good performance in the independent test set.

Impact: We propose an algorithm that can help with the tedious radiological task of detecting cerebral microbleeds in the brain. We further demonstrate that a model trained solely on simulated bleeds can effectively detect actual microbleeds in real MRI data.

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Keywords