Abstract #1449

Initial experience in pCASL using a novel neurovascular coil at 7T

Janhavi S Ghosalkar¹, Belinda Ding², Chenyang Zhao³, Graeme A Keith¹, Divya Baskaran¹, Rosiee Woodward¹, Samantha J Ma⁴, Sydney Williams¹, Keith Muir⁵, Shajan Gunamony ^1,6, Danny J J Wang³, and David Porter¹

¹Imaging Centre of Excellence, University of Glasgow, Glasgow, Scotland, ²Siemens Healthcare Ltd, Glasgow, Scotland, ³University of Southern California, Los Angeles, CA, United States, ⁴Siemens Healthineers USA, Los Angeles, CA, United States, ⁵University of Glasgow, Glasgow, Scotland, ⁶MR Coil Tech, Glasgow, Scotland

Synopsis

Keywords: High-Field MRI, RF Arrays & Systems

Motivation: Labeling efficiency in pCASL suffers from an inferior drop-off in B1+ leading to low SNR perfusion-weighted images which can affect CBF quantification.

Goal(s): To assess the feasibility of pCASL in healthy volunteers using a custom-built head and neck coil at 7T.

Approach: Volunteers were scanned with pCASL on two coils: a normal head coil and a head and neck coil with circularly polarized shim weights, and the results were compared in terms of CBF and tSNR.

Results: pCASL in healthy volunteers using a novel neurovascular coil at 7T gave an average GM/WM CBF ratio of 1.51, comparable to a conventional head coil.

Impact: This proof-of-concept study shows the feasibility of pCASL using a novel 8TxRx56Rx neurovascular (head and neck) coil at 7T and compares the performance against a conventional 8Tx64Rx head coil.

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