(ISMRM 2024) Cardiovascular MR Multitasking T1-T2 Joint Mapping in Healthy Subjects and Cardiomyopathy Patients on both 1.5T and 3T
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Abstract #1484

Cardiovascular MR Multitasking T1-T2 Joint Mapping in Healthy Subjects and Cardiomyopathy Patients on both 1.5T and 3T

Xianglun Mao1, Hsu-Lei Lee2, Katerina Eyre3, Debiao Li2,4, Anthony G Christodoulou4,5, Matthias G Friedrich3,6, Michael Salerno7, and Martin A Janich8
1Applied Science Lab West, GE HealthCare, Menlo Park, CA, United States, 2Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, 3McGill University Health Centre, Mentreal, QC, Canada, 4Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA, United States, 5Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States, 6Area 19, Montreal, QC, Canada, 7Departments of Medicine and Radiology, Stanford University, Palo Alto, CA, United States, 8Applied Science Lab Europe, GE HealthCare, Munich, Germany

Synopsis

Keywords: Myocardium, Quantitative Imaging, Free-breathing, Multi-parametric Mapping

Motivation: CMR Multitasking has shown promise for non-ECG and free-breathing myocardial T1/T2 mapping in the heart, primarily on a single vendor 3T, but 2D T1-T2 CMR Multitasking has not yet been shown for different vendors (e.g., GE) and field strengths (e.g., 1.5T).

Goal(s): To extend 2D T1-T2 CMR Multitasking to 1.5T and 3.0T GE MR systems.

Approach: We implemented a 2D T1-T2 CMR Multitasking sequence on GE MR systems and evaluated its performance in healthy volunteers and patients at two sites.

Results: 2D T1-T2 CMR Multitasking generated T1 and T2 maps with image quality comparable to the reference measurements.

Impact: 2D T1-T2 CMR Multitasking provides an efficient and subject friendly (free-breathing, non-ECG) option for quantitative CMR assessment across sites and vendors.

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