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Abstract #1487

Free-breathing 3D whole-heart simultaneous bright- and black-blood anatomical imaging and T1/T2 mapping at 0.55T

Ivan Kokhanovskyi1,2,3,4, Carlos Castillo-Passi3,4,5, Michael G. Crabb3, Carl Ganter1, Karl P. Kunze3,6, Radhouene Neji3, Dimitrios Karampinos1, Marcus R. Makowski1,2, Claudia Prieto3,4,7, and Rene M. Botnar2,3,4,5,7
1Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 2Institute for Advanced Study, Technical University of Munich, Munich, Germany, 3School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 4Millenium Institute for intelligent Healthcare Engineering, Santiago, Chile, 5Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 6MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, 7School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Myocardium, Heart, Bright- and black-blood imaging, T1/T2 mapping

Motivation: To overcome the limitations of clinical examinations, which require several sequential acquisitions under multiple breath-holds, and to make cardiac MR more accessible and affordable at lower field strength.

Goal(s): To develop a novel 3D free-breathing sequence for simultaneous assessment of cardiovascular anatomy via bright- and black-blood imaging and myocardial tissue quantification in an easy to use one-click-scan at 0.55T.

Approach: Implementation of a novel iNAV-based 5-heartbeat interleaved sequence (proACTION) with distinct IR and T2 preparation modules and non-rigid motion correction at 0.55T.

Results: proACTION provides good delineation of cardiac and vascular structures with accurate joint T1/T2 parametrical mapping in healthy subjects.

Impact: Comprehensive 3D whole-heart evaluation of cardiovascular anatomy and tissue characterization with T1/T2 maps can be obtained in an efficient, free-breathing, and easier to use one-click-scan with proACTION at 0.55T.

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