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Abstract #1522

Acceleration of IR-prepared Ultra Short Echo Time Imaging of Bones exploiting a Plug-and-Play Denoising Prior

Philipp Hans Nunn1, Oliver Schad1, Jan-Peter Grunz1, Johannes Tran-Gia2, and Tobias Wech1
1Department of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, 2Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany

Synopsis

Keywords: Bone, Bone, Plug-and-Play Denoiser, IR-UTE, AI and Machine Learning

Motivation: (IR-)UTE MRI enables (quantitative) investigation of bony tissue. Imaging protocols, however, are still time consuming.

Goal(s): To develop a reconstruction method, which can transfer undersampled / accelerated IR-UTE scans of bone into high quality images.

Approach: A thresholded Landweber algorithm was implemented, which uses both an L1-sparsity model and a pre-trained denoising convolutional network as regularizers of the physical MR model.

Results: The reconstruction method was capable of delivering superior image quality compared to reconstructions based on straightforward NUFFT or iterative SENSE, especially in the case of significant undersampling.

Impact: IR-UTE imaging accelerated by our proposed reconstruction based on L1-sparsity and a pre-trained denoising convolutional neural network shortens investigations by a factor of up to five, thereby facilitating further research on the topic as well as clinical transfer.

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Keywords