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Abstract #1602

A Simulation Framework for Comparison of Volumetric B1+ Mapping Methods

James L. Kent1, Ladislav Valkovič2,3, Iulius Dragonu4, and Aaron T. Hess1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Oxford Centre for Clinical Magnetic Resonance Research, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom, 3Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia, 4Research & Collaborations GB&I, Siemens Healthcare Ltd, Frimley, United Kingdom

Synopsis

Keywords: High-Field MRI, High-Field MRI, B1+ Mapping, SatTFL, AFI, DREAM, Sandwich, SA2RAGE

Motivation: To benefit from all the advantages that ultra-high field MRI offers, knowledge of the RF transmit field (B1+) is required. Many B1+ mapping methods have been developed, but no single method has become the ‘gold-standard’, with many sites opting for their own implementations.

Goal(s): To evaluate five promising sequences and understand their sensitivity to B0, T1, flow and SNR on the accuracy and dynamic range of the measured B1+.

Approach: SatTFL, Sandwich, SA2RAGE, AFI, and 3DREAM were investigated in MATLAB using open-source EPG and Bloch simulations.

Results: A simulation framework to compare B1+ mapping sequences was developed.

Impact: This simulation framework is beneficial for understanding the impact of various factors on the accuracy of B1+ mapping sequences and can help to inform better pulse sequence design and parameter optimisation.

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Keywords