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Abstract #1633

Evaluating Muscle Health with Multiparametric MRI after FES-Bike Exercise Training in People with Spinal Cord Injury

Alfonso Mastropietro1, Maria Giovanna Taccogna2, Denis Peruzzo3, Nicole Sanna4, Roberta Nossa3, Alessandra Pedrocchi5, Emilia Ambrosini5, Emilia Biffi3, and Giovanna Rizzo1
1Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato, Consiglio Nazionale delle Ricerche, Milano, Italy, 2Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche, Segrate, Italy, 3Neuroimaging Unit, Scientific Institute IRCCS “Eugenio Medea”, Bosisio Parini (LC), Italy, 4Department of Mechanical Engineering, Politecnico di Milano, Milano, Italy, 5Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy

Synopsis

Keywords: Muscle, Muscle, Multi parametric MRI; Quantitative MRI; Rehabilitation

Motivation: Our research is driven by the need for advanced, non-invasive tools to assess the rehabilitation effectiveness in people with Spinal Cord Injury (SCI).

Goal(s): To determine the effects of Functional Electrical Stimulation (FES)-bike exercise training on muscle health in SCI patients using multiparametric MRI (mpMRI).

Approach: Four males with SCI conducted a 12-week FES-bike exercise training program. mpMRI was used to assess muscle health comprehensively considering muscle volume, fat fraction, diffusion parameters.

Results: Our study demonstrated significant increase in muscle volume and decrease in fat infiltration in the thigh muscles of people with SCI after 12-weeks of FES-bike training.

Impact: Our study highlights the potential of mpMRI for assessing the effectiveness of FES-bike training in people with SCI. This paves the way for more comprehensive evaluation methods, fostering precise monitoring of muscle health during rehabilitation and promoting tailored treatment strategies.

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