Abstract #1633

Evaluating Muscle Health with Multiparametric MRI after FES-Bike Exercise Training in People with Spinal Cord Injury

Alfonso Mastropietro¹, Maria Giovanna Taccogna², Denis Peruzzo³, Nicole Sanna⁴, Roberta Nossa³, Alessandra Pedrocchi⁵, Emilia Ambrosini⁵, Emilia Biffi³, and Giovanna Rizzo¹

¹Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato, Consiglio Nazionale delle Ricerche, Milano, Italy, ²Istituto di Tecnologie Biomediche, Consiglio Nazionale delle Ricerche, Segrate, Italy, ³Neuroimaging Unit, Scientific Institute IRCCS “Eugenio Medea”, Bosisio Parini (LC), Italy, ⁴Department of Mechanical Engineering, Politecnico di Milano, Milano, Italy, ⁵Department of Electronics, Information and Bioengineering, Politecnico di Milano, Milano, Italy

Synopsis

Keywords: Muscle, Muscle, Multi parametric MRI; Quantitative MRI; Rehabilitation

Motivation: Our research is driven by the need for advanced, non-invasive tools to assess the rehabilitation effectiveness in people with Spinal Cord Injury (SCI).

Goal(s): To determine the effects of Functional Electrical Stimulation (FES)-bike exercise training on muscle health in SCI patients using multiparametric MRI (mpMRI).

Approach: Four males with SCI conducted a 12-week FES-bike exercise training program. mpMRI was used to assess muscle health comprehensively considering muscle volume, fat fraction, diffusion parameters.

Results: Our study demonstrated significant increase in muscle volume and decrease in fat infiltration in the thigh muscles of people with SCI after 12-weeks of FES-bike training.

Impact: Our study highlights the potential of mpMRI for assessing the effectiveness of FES-bike training in people with SCI. This paves the way for more comprehensive evaluation methods, fostering precise monitoring of muscle health during rehabilitation and promoting tailored treatment strategies.

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