Keywords: Myocardium, Myocardium
Motivation: Early detection of cardiac involvement and continuous monitoring of disease progression could benefit patients with light-chain amyloidosis. The application of left ventricular strain by Cardiac magnetic resonance feature tracking imaging has emerged as an excellent noninvasive imaging modality.
Goal(s): This study is dedicated to exploring the prognostic implications of myocardial strain in distinct myocardial segments.
Approach: The assessment of both global and segmental myocardial strain was conducted through the application of steady-state free precession (SSFP) cine sequences.
Results: Global radial strain (RSglobal), RS in the basal lateral segment (RSbas-lateral) and B-type natriuretic peptides (BNP) are independently associated with all-cause mortality.
Impact: Quantification of LV strain could be employed to monitor the progression of amyloid light-chain (AL) amyloidosis. Global radial strain and radial strain in the basal lateral segment may prove valuable for risk stratification in patients with AL amyloidosis.
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