Keywords: Myocardium, Cardiovascular
Motivation: People living with HIV are at increased risk of cardiovascular disease compared with healthy people.
Goal(s): To explore the extent of diastolic atrial and left ventricular dysfunction in PLWH by CMR in correlation with clinical markers of disease activity.
Approach: 101 PLWH and 62 healthy volunteers were recruited for this study in China. Both left atrial (LA) and LV strain and strain rate were calculated using CMR feature tracking.
Results: PLWH had a larger LAVImax, LAVImin and LAVIpre-a as compared to healthy volunteers. The LA
reservoir, conduit and booster pump function were all impaired in PLWH.
Impact: The prevalence of diastolic dysfunction as well as asymptomatic systolicabnormalities is observed in HIV patients.
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