Keywords: Myocardium, Cardiovascular, 3D real-time imaging
Motivation: To achieve high-temporal-resolution 3D whole-heart MR cine without the need for ECG, allow direct visualization of physiological motions, and assess cardiac function in clinical practice.
Goal(s): To attain 3D multi-slice whole-heart real-time imaging with <50 ms temporal resolution, while preserving adequate spatial resolution for cardiac functional analysis.
Approach: We employed golden-angle rotated spiral-in/out trajectory with 32× acceleration, and randomized variable density kz phase-encoding in the bSSFP sequence, and harnessed an iterative reconstruction algorithm.
Results: We attained a groundbreaking achievement in advancing MRI capabilities, obtaining an ECG-free 3D real-time cardiac cine with complete 12-slice whole-heart coverage and an impressive sub-50 ms temporal resolution.
Impact: We've employed advanced techniques to triumph over MRI's historical disadvantage of slower acquisition compared to other modalities. Pioneering a groundbreaking approach, we achieve high temporal resolution for 3D real-time imaging without ECG, breath-holding, or data segmentation, revolutionizing cardiac motion capture.
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