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Abstract #1675

The Feasibility of Analyzing Systolic and Diastolic Myocardial Volume Ratio Based on CMR to Evaluate Myocardial Fibrosis in HCM Patients

Haishan Wu1, Pengfei Liu1, Xinyu Zhu1, and Jianxiu Lian2
1The First Afliated Hospital of Harbin Medical University, Harbin, China, 2Philips Healthcare, Beijing, China

Synopsis

Keywords: Myocardium, Cardiomyopathy

Motivation: CMR, the gold standard for diagnosing myocardial diseases, is known for its ability to assess local myocardial fibrosis through LGE imaging. However, this imaging technique requires a contrast agent, limiting its use in patients with allergies or renal dysfunction.

Goal(s): The purpose of this study is to assess the ability of MVs/MVd as a new indicator to measure the extent of myocardial fibrosis.

Approach: Explore the correlation between MVs/MVd and LGE% in patients with hypertrophic cardiomyopathy.

Results: The results indicate that MVs/MVd may possess the ability to indicate myocardial fibrosis without the need for a contrast agent.

Impact: MVs/MVd, in contrast to traditional methods, directly measures the entire cardiac cycle, offering valuable insights into myocardial properties. Importantly, it can gauge myocardial fibrosis to some extent without requiring a contrast agent, making it clinically significant for diagnosis and treatment.

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