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Abstract #1676

Insights from CMR Parameters and their Association with NT-proBNP Levels, A Retrospective Analysis.

Rui Zhang1, Yanhui Hao1, Yi Zhu2, and Jianxin Guo1
1The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China, 2Philips Healthcare, Beijing, China

Synopsis

Keywords: Heart Failure, Cardiovascular

Motivation: To investigate the potential of different CMR parameters as non-invasive, indirect indicators of NT-proBNP levels in HEpEF patients and to assess their utility in enhancing disease prognosis and assessment.

Goal(s): The objective of this study is to explore the relationship between NT-proBNP and left ventricular functional parameters, T1 mapping, ECV, and myocardial strain parameters in CMR.

Approach: A retrospective study was conducted with a cohort of HEpEF patients. Advanced cardiac MRI techniques were utilized to ascertain each CMR parameter.

Results: A notable correlation was discerned between myocardial stress parameters and Native T1 values with serum NT-proBNP levels.

Impact: NT-proBNP is a fundamental biomarker for assessing and predicting alterations in left ventricular function. Myocardial stress parameters and Native T1 showcase potential as non-invasive indicators.Future research must focus on multi-center, prospective studies to validate and expand on these findings.

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