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Abstract #1691

Differentiating Between Malignant and Benign Bone Tumors: Combined Diagnostic Value of DWI, IVIM and DKI

Ying Li 1, Cuiping Ren1, Wenhua Zhang1, Jingliang Cheng1, Dandan Zheng2, and Liangjie Lin2
1The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China, 2Clinical & Technical Support, Philips Healthcare, Beijing, 100102, China, Beijing, China

Synopsis

Keywords: Other Musculoskeletal, Tumor

Motivation: The integration of various diffusion models can yield more precise insights into tumor diffusion and perfusion.

Goal(s): To investigate the utility of combining DWI, IVIM and DKI in the differential diagnosis of benign and malignant bone tumors.

Approach: Six parameters derived from three diffusion models of 107 patients were statistically compared through either the independent samples t-test or Mann-Whitney U test. Diagnostic performance was assessed using ROC curves for both individual examinations and their combined analysis in distinguishing between benign and malignant tumors.

Results: The combination of ADC, D, D*, MK, and MD values had better diagnostic efficacy than these parameters alone.

Impact: Statistically significant differences were observed in the values of ADC, D, D*, MD, and MK between benign and malignant bone tumors. Furthermore, the combination of ADC, D, D*, MK, and MD values had better diagnostic efficacy than these parameters alone.

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