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Abstract #1705

Using deep learning to predict muscle function based on anatomical MRI scans from the OAI and SOMMA datasets

Bragi Sveinsson1,2, Vijaya Kolachalama3,4, Evelyn Hsieh5,6, and David Felson3,5
1Athinoula A. Martinos Center for Biomedical Imaging, Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Radiology, Harvard Medical School, Boston, MA, United States, 3Medicine, Boston University, Boston, MA, United States, 4Computer Science and Faculty of Computing & Data Sciences, Boston University, Boston, MA, United States, 5Section of Rheumatology, Yale School of Medicine, New Haven, CT, United States, 6Section of Rheumatology, VA Connecticut Healthcare System, West Haven, CT, United States

Synopsis

Keywords: Muscle, Muscle, Data Analysis, MSK

Motivation: Estimating physical performance including muscle function is conventionally done by having a subject complete physical tasks. MRI-based estimates leveraging deep learning could complement such measures.

Goal(s): To investigate the feasibility of predicting measures physical performance including muscle strength from MRI scans of the leg using deep learning.

Approach: We used large MRI databases (OAI and SOMMA) to train a neural network for classification into high or low physical performance. We also tried the method on a small prospective cohort.

Results: We obtained over 70% accuracy for estimating high or low muscle function, indicating high predictive power.

Impact: We demonstrate the feasibility of predicting muscle function from anatomical MRI scans using deep learning, leveraging advances in deep learning and musculoskeletal MRI databases that include functional measures. Such MRI-based predictions could complement conventional methods for estimating muscle function.

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Keywords