Abstract #1707

T2-Weighted MR Neurography and Muscle Evaluation Using GRAPPATINI T2 Mapping

Amy Z. Lu^1,2, Yenpo Lin^2,3, Tom Hilbert^4,5,6, Xiaoying Cai⁷, Darryl B. Sneag², and Ek T. Tan²

¹Weill Cornell Medicine, New York, NY, United States, ²Department of Radiology and Imaging, Hospital for Special Surgery, New York, NY, United States, ³Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou, Taiwan, ⁴Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, ⁵Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, ⁶LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, ⁷Siemens Medical Solutions USA, Inc., New York, NY, United States

Synopsis

Keywords: Neurography, Nerves, Muscle

Motivation: To evaluate the feasibility and reliability of an accelerated T2 mapping technique (GRAPPATINI) for MR neurography and muscle evaluation.

Goal(s): The study aims to qualitatively and quantitatively evaluate GRAPPATINI for MR neurography in patients with foot drop.

Approach: To compare the image quality from GRAPPATINI T2-weighted images against conventional T2-weighted images, and to compare T2 values between abnormal and normal muscles.

Results: No significant qualitative differences were observed between GRAPPATINI and conventional images diagnostically; there was complete agreement in assessment of nerve signal hyperintensity and size, and muscle edema. Significant differences in GRAPPATINI T2 values were observed between abnormal and normal muscles.

Impact: In one acquisition, GRAPPATINI can simultaneously provide clinically equivalent qualitative information and quantitative T2 maps for MR neurography evaluation of foot drop.

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